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Analytical validation of Aspyre Clinical Test for Lung (Blood): A multiplexed PCR and pyrophosphorolysis-based assay for detecting actionable NSCLC variants in plasma cfDNA and cfRNA.

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Title: Analytical validation of Aspyre Clinical Test for Lung (Blood): A multiplexed PCR and pyrophosphorolysis-based assay for detecting actionable NSCLC variants in plasma cfDNA and cfRNA.
Authors: Evans RT; Biofidelity Inc., Morrisville, NC, USA., Knudsen KE; Biofidelity Inc., Morrisville, NC, USA., Gillon-Zhang E; Biofidelity Inc., Morrisville, NC, USA., Brown JN; Biofidelity Inc., Morrisville, NC, USA., King C; Biofidelity Inc., Morrisville, NC, USA., Rossi MB; Biofidelity Inc., Morrisville, NC, USA., Kiser C; Biofidelity Inc., Morrisville, NC, USA., Schaffernoth JA; Biofidelity Inc., Morrisville, NC, USA., Green AS; Biofidelity Inc., Morrisville, NC, USA., Silva AL; Biofidelity Ltd., Cambridge, United Kingdom., von Bargen K; Biofidelity Ltd., Cambridge, United Kingdom., Mordaka JM; Biofidelity Ltd., Cambridge, United Kingdom., Palmer RN; Biofidelity Ltd., Cambridge, United Kingdom., Tomassini A; Biofidelity Ltd., Cambridge, United Kingdom., Collazos A; Biofidelity Ltd., Cambridge, United Kingdom., Andreazza S; Biofidelity Ltd., Cambridge, United Kingdom., Turner I; Biofidelity Ltd., Cambridge, United Kingdom., Ho CH; Biofidelity Ltd., Cambridge, United Kingdom., Nugent D; Biofidelity Ltd., Cambridge, United Kingdom., Jose J; Biofidelity Ltd., Cambridge, United Kingdom., Xyrafaki C; Biofidelity Inc., Morrisville, NC, USA., Barot P; Biofidelity Ltd., Cambridge, United Kingdom., Stolarek-Januszkiewicz M; Biofidelity Ltd., Cambridge, United Kingdom., Abujudeh S; Biofidelity Ltd., Cambridge, United Kingdom., Gray ER; Biofidelity Ltd., Cambridge, United Kingdom., Gregg J; Biofidelity Inc., Morrisville, NC, USA., Levin WJ; Biofidelity Inc., Morrisville, NC, USA., Balmforth BW; Biofidelity Ltd., Cambridge, United Kingdom., Pitts K; Biofidelity Inc., Morrisville, NC, USA., Brown S; Biofidelity Inc., Morrisville, NC, USA.
Source: The journal of liquid biopsy [J Liq Biopsy] 2025 May 15; Vol. 8, pp. 100298. Date of Electronic Publication: 2025 May 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: United States NLM ID: 9918957761506676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-1954 (Electronic) Linking ISSN: 29501954 NLM ISO Abbreviation: J Liq Biopsy Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2950-1954
DOI:10.1016/j.jlb.2025.100298