Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition.
Saved in:
| Title: | Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition. |
|---|---|
| Authors: | Fischer J; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany. julia.fischer2@ukmuenster.de.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany. julia.fischer2@ukmuenster.de.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany. julia.fischer2@ukmuenster.de.; University of Münster, Faculty of Medicine and University Hospital of Münster, Department of Internal Medicine B, Albert-Schweitzer-Campus, Münster, Germany. julia.fischer2@ukmuenster.de., Rusyn L; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany., Krus F; University of Münster, Faculty of Medicine and University Hospital of Münster, Department of Internal Medicine B, Albert-Schweitzer-Campus, Münster, Germany., Lobastova L; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Chair Translational Research, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Herb M; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Institute of Medical Microbiology, Immunology and Hygiene, Cologne, Germany., Gluschko A; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Institute of Medical Microbiology, Immunology and Hygiene, Cologne, Germany., Hejazi Z; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Hos NJ; Department of Clinical Research, Clinic of Infectious Diseases, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, United Kingdom., Calabrese C; Max Planck Institute for Biology of Ageing, Cologne, Germany., Stemler J; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.; Department II of Internal Medicine, Hematology/Oncology and Infectious Diseases, University Hospital of Frankfurt, Frankfurt, Germany., Mayer P; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany., Hanssen R; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Policlinic for Endocrinology, Diabetes and Preventive Medicine, Cologne, Germany.; Max Planck Institute for Metabolism Research, Cologne, Germany., Theobald SJ; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Vehreschild JJ; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.; Department II of Internal Medicine, Hematology/Oncology and Infectious Diseases, University Hospital of Frankfurt, Frankfurt, Germany., Trebicka J; University of Münster, Faculty of Medicine and University Hospital of Münster, Department of Internal Medicine B, Albert-Schweitzer-Campus, Münster, Germany.; European Foundation for the Study of Chronic Liver Failure - EF Clif, Barcelona, Spain.; Institute for Bioengineering of Catalonia, Barcelona, Spain.; Department of Medical Gastroenterology and Hepatology, University of Southern Denmark, Odense, Denmark., Krönke M; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Chair Translational Research, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Institute of Medical Microbiology, Immunology and Hygiene, Cologne, Germany., Fries JWU; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Institute of Pathology, University of Cologne, Cologne, Germany., Lehmann C; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Nguyen PH; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Chair Translational Research, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Rybniker J; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany.; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Robinson N; Center for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia.; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia., Seeger-Nukpezah T; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Department I of Internal Medicine, Center for Integrated Oncology, Cologne, Germany. tamina.seeger-nukpezah@uk-koeln.de. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Jun 12; Vol. 16 (1), pp. 445. Date of Electronic Publication: 2025 Jun 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2041-4889 |
|---|---|
| DOI: | 10.1038/s41419-025-07634-9 |
