Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation.

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Title: Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation.
Authors: Kristof A; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Karunakaran K; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Allen C; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Mizote P; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Briggs S; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Jian Z; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Nash P; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Blazeck J; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA. john.blazeck@chbe.gatech.edu.
Source: Genome biology [Genome Biol] 2025 Jun 12; Vol. 26 (1), pp. 164. Date of Electronic Publication: 2025 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-760X
DOI:10.1186/s13059-025-03640-4