Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients.
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| Title: | Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients. |
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| Authors: | Bouchereau E; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Pruvost-Robieux E; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Siami S; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France., Chaffaut C; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France., Bouglé A; Department of Anesthesiology and Critical Care Medicine, Cardiology Institute, Sorbonne University, GRC 29, AP-HP, Pitié-Salpêtrière Hospital, Paris, France., Gavaret M; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Heming N; General Intensive Care Unit, APHP, Raymond Poincaré Hospital, University of Versailles Saint-Quentin en Yvelines, Garches, France., Sivanandamoorthy S; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France., Zyss J; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Degos V; Department of Anesthesiology and Critical Care, Sorbonne University, AP-HP, Pitié Salpêtrière - Charles Foix Hospital, Paris, France., Kandelman S; Department of Anesthesiology, Royal Victoria Hospital, McGill University Health Center, Montreal, Canada., Righy Shinotsuka C; Department of Neurointensive Care, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.; Laboratório de Medicina Intensiva, Fundação Oswaldo Cruz, Instituto Nacional de Infectologia, Rio de Janeiro, Brazil., Benghanem S; Medical Intensive Care Unit, Cochin Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France., Naccache L; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Rohaut B; Department of Neurology, Neuro-ICU & Brain Institute - ICM, Pitié-Salpêtrière Hospital APHP, Sorbonne Université, Paris, France., Hermann B; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.; Medical Intensive Care Unit, HEGP Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France., Azabou E; Department of Physiology and Department of Critical Care Medicine, Inserm UMR 1173 Infection and Inflammation, Raymond Poincaré Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), University of Versailles Saint Quentin (UVSQ), University Paris-Saclay, Garches, Paris, France., Chevret S; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France., Sharshar T; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France. t.sharshar@ghu-paris.fr.; Neuro-Anesthesiology and Intensive Care Medicine, GHU-Paris Psychiatrie Et Neurosciences, Université de Paris, Paris, France. t.sharshar@ghu-paris.fr. |
| Source: | Intensive care medicine [Intensive Care Med] 2025 Jun; Vol. 51 (6), pp. 1050-1061. Date of Electronic Publication: 2025 Jun 13. |
| Publication Type: | Journal Article; Observational Study; Multicenter Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1238 |
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| DOI: | 10.1007/s00134-025-07945-7 |
