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Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients.

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Title: Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients.
Authors: Bouchereau E; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Pruvost-Robieux E; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Siami S; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France., Chaffaut C; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France., Bouglé A; Department of Anesthesiology and Critical Care Medicine, Cardiology Institute, Sorbonne University, GRC 29, AP-HP, Pitié-Salpêtrière Hospital, Paris, France., Gavaret M; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France., Heming N; General Intensive Care Unit, APHP, Raymond Poincaré Hospital, University of Versailles Saint-Quentin en Yvelines, Garches, France., Sivanandamoorthy S; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France., Zyss J; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Degos V; Department of Anesthesiology and Critical Care, Sorbonne University, AP-HP, Pitié Salpêtrière - Charles Foix Hospital, Paris, France., Kandelman S; Department of Anesthesiology, Royal Victoria Hospital, McGill University Health Center, Montreal, Canada., Righy Shinotsuka C; Department of Neurointensive Care, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.; Laboratório de Medicina Intensiva, Fundação Oswaldo Cruz, Instituto Nacional de Infectologia, Rio de Janeiro, Brazil., Benghanem S; Medical Intensive Care Unit, Cochin Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France., Naccache L; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Rohaut B; Department of Neurology, Neuro-ICU & Brain Institute - ICM, Pitié-Salpêtrière Hospital APHP, Sorbonne Université, Paris, France., Hermann B; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.; Medical Intensive Care Unit, HEGP Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France., Azabou E; Department of Physiology and Department of Critical Care Medicine, Inserm UMR 1173 Infection and Inflammation, Raymond Poincaré Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), University of Versailles Saint Quentin (UVSQ), University Paris-Saclay, Garches, Paris, France., Chevret S; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France., Sharshar T; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France. t.sharshar@ghu-paris.fr.; Neuro-Anesthesiology and Intensive Care Medicine, GHU-Paris Psychiatrie Et Neurosciences, Université de Paris, Paris, France. t.sharshar@ghu-paris.fr.
Source: Intensive care medicine [Intensive Care Med] 2025 Jun; Vol. 51 (6), pp. 1050-1061. Date of Electronic Publication: 2025 Jun 13.
Publication Type: Journal Article; Observational Study; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients.
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  Data: <searchLink fieldCode="AU" term="%22Bouchereau+E%22">Bouchereau E</searchLink>; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pruvost-Robieux+E%22">Pruvost-Robieux E</searchLink>; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Siami+S%22">Siami S</searchLink>; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France.<br /><searchLink fieldCode="AU" term="%22Chaffaut+C%22">Chaffaut C</searchLink>; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bouglé+A%22">Bouglé A</searchLink>; Department of Anesthesiology and Critical Care Medicine, Cardiology Institute, Sorbonne University, GRC 29, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gavaret+M%22">Gavaret M</searchLink>; Department of Clinical Neurophysiology, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Heming+N%22">Heming N</searchLink>; General Intensive Care Unit, APHP, Raymond Poincaré Hospital, University of Versailles Saint-Quentin en Yvelines, Garches, France.<br /><searchLink fieldCode="AU" term="%22Sivanandamoorthy+S%22">Sivanandamoorthy S</searchLink>; General Intensive Care Unit, Sud-Essonne Hospital, Etampes, France.<br /><searchLink fieldCode="AU" term="%22Zyss+J%22">Zyss J</searchLink>; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Degos+V%22">Degos V</searchLink>; Department of Anesthesiology and Critical Care, Sorbonne University, AP-HP, Pitié Salpêtrière - Charles Foix Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kandelman+S%22">Kandelman S</searchLink>; Department of Anesthesiology, Royal Victoria Hospital, McGill University Health Center, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Righy+Shinotsuka+C%22">Righy Shinotsuka C</searchLink>; Department of Neurointensive Care, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.; Laboratório de Medicina Intensiva, Fundação Oswaldo Cruz, Instituto Nacional de Infectologia, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Benghanem+S%22">Benghanem S</searchLink>; Medical Intensive Care Unit, Cochin Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France.<br /><searchLink fieldCode="AU" term="%22Naccache+L%22">Naccache L</searchLink>; Department of Clinical Neurophysiology, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Rohaut+B%22">Rohaut B</searchLink>; Department of Neurology, Neuro-ICU & Brain Institute - ICM, Pitié-Salpêtrière Hospital APHP, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hermann+B%22">Hermann B</searchLink>; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France.; Institute of Psychiatry, Neurosciences of Paris, INSERM U1266, Université Paris Cité, Paris, France.; Medical Intensive Care Unit, HEGP Hospital, Assistance Publique - Hôpitaux de Paris-Centre (APHP-Centre), Paris, France.<br /><searchLink fieldCode="AU" term="%22Azabou+E%22">Azabou E</searchLink>; Department of Physiology and Department of Critical Care Medicine, Inserm UMR 1173 Infection and Inflammation, Raymond Poincaré Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), University of Versailles Saint Quentin (UVSQ), University Paris-Saclay, Garches, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chevret+S%22">Chevret S</searchLink>; Department of Biostatistics, Hôpital Saint-Louis, AP-HP, Paris, France.; Université Paris Cité, Inserm UMR 1153, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sharshar+T%22">Sharshar T</searchLink>; Anesthesia and Intensive Care Department, GHU Paris Psychiatrie et Neurosciences, Pole Neuro, Sainte‑Anne Hospital, Paris, France. t.sharshar@ghu-paris.fr.; Neuro-Anesthesiology and Intensive Care Medicine, GHU-Paris Psychiatrie Et Neurosciences, Université de Paris, Paris, France. t.sharshar@ghu-paris.fr.
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  Data: <searchLink fieldCode="JN" term="%227704851%22">Intensive care medicine</searchLink> [Intensive Care Med] 2025 Jun; Vol. 51 (6), pp. 1050-1061. <i>Date of Electronic Publication: </i>2025 Jun 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7704851 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203424642%22">03424642 </searchLink><i>NLM ISO Abbreviation: </i>Intensive Care Med <i>Subsets: </i>MEDLINE
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