REcovery from DEXmedetomidine-Induced Unresponsiveness (REDEX): A Study Protocol for a Single Center, Parallel Arm, Non-Randomized, Controlled Pilot Trial in Healthy Volunteers.

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Title: REcovery from DEXmedetomidine-Induced Unresponsiveness (REDEX): A Study Protocol for a Single Center, Parallel Arm, Non-Randomized, Controlled Pilot Trial in Healthy Volunteers.
Authors: Schreier DR; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland., Fecchio M; Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Guay CS; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Anesthesiology, Perioperative and Pain Medicine, The University of Utah, Salt Lake City, UT, USA., Kovacs RG; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Olchanyi M; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Mueller AL; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA., Houle TT; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA., Edlow BL; Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA., Brown EN; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Solt K; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, USA.
Source: Nature and science of sleep [Nat Sci Sleep] 2025 Jun 12; Vol. 17, pp. 1259-1269. Date of Electronic Publication: 2025 Jun 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101537767 Publication Model: eCollection Cited Medium: Print ISSN: 1179-1608 (Print) Linking ISSN: 11791608 NLM ISO Abbreviation: Nat Sci Sleep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1179-1608
DOI:10.2147/NSS.S523111