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Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity.

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Title: Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity.
Authors: Howden JH; Neuroscience, Physiology and Pharmacology, University College London, London, UK., Hakansson H; Neuroscience, Physiology and Pharmacology, University College London, London, UK., Nieto-Rostro M; Neuroscience, Physiology and Pharmacology, University College London, London, UK., McAdam R; Neuroscience, Biopharmaceutical R&D, AstraZeneca, Cambridge, UK., Arber C; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Brandon NJ; Neuroscience, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Kittler JT; Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address: j.kittler@ucl.ac.uk.
Source: Cell reports [Cell Rep] 2025 Jun 24; Vol. 44 (6), pp. 115809. Date of Electronic Publication: 2025 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity.
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  Data: <searchLink fieldCode="AU" term="%22Howden+JH%22">Howden JH</searchLink>; Neuroscience, Physiology and Pharmacology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hakansson+H%22">Hakansson H</searchLink>; Neuroscience, Physiology and Pharmacology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Nieto-Rostro+M%22">Nieto-Rostro M</searchLink>; Neuroscience, Physiology and Pharmacology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22McAdam+R%22">McAdam R</searchLink>; Neuroscience, Biopharmaceutical R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Arber+C%22">Arber C</searchLink>; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Brandon+NJ%22">Brandon NJ</searchLink>; Neuroscience, IMED Biotech Unit, AstraZeneca, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kittler+JT%22">Kittler JT</searchLink>; Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address: j.kittler@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2025 Jun 24; Vol. 44 (6), pp. 115809. <i>Date of Electronic Publication: </i>2025 Jun 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101573691 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-1247 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Rep <i>Subsets: </i>MEDLINE
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