It's a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies.

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Title: It's a match: use of the radionuclide theranostic pair 133La/225Ac for the radiopharmacological characterization of EGFR-targeted single-domain antibodies.
Authors: Trommer J; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Ullrich M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Reissig F; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Brühlmann SA; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Nitt-Weber AK; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Novy Z; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.; Czech Advanced Technology and Research Institute, Palacký University, Olomouc, Czech Republic., Hajduova K; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic., Kurfurstova D; Institute of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic., Hendrychova R; Institute of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic., Bouchal J; Institute of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic., Petrik M; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.; Czech Advanced Technology and Research Institute, Palacký University, Olomouc, Czech Republic.; Laboratory of Experimental Medicine, University Hospital, Olomouc, Czech Republic., Neuber C; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Sihver W; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Stadlbauer S; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Pietzsch J; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technische Universität Dresden, Dresden, Germany., Kreller M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany., Kopka K; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technische Universität Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT) Dresden, University Hospital Carl Gustav Carus, Fetscherstraße 74, 01307, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Fetscherstraße 74, 01307, Dresden, Germany., Mamat C; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technische Universität Dresden, Dresden, Germany., Zarschler K; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany. k.zarschler@hzdr.de.
Source: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2025 Jun 19; Vol. 10 (1), pp. 31. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2365-421X
DOI:10.1186/s41181-025-00354-7