ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism.

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Title: ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism.
Authors: Rashan EH; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Bartlett AK; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA., Khana DB; Department of Microbiology, University of Wisconsin-Madison, Madison, WI, USA., Zhang J; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Jain R; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Wade G; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Abriata LA; Laboratory for Biomolecular Modeling and Protein Structure Core Facility, School of Life Sciences, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Smith AJ; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA., Baker ZN; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA., Cook T; Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA., Caldwell A; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Chevalier AR; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Forny P; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA., Pfleger BF; Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA., Peraro MD; Laboratory for Biomolecular Modeling and Protein Structure Core Facility, School of Life Sciences, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Yuan P; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Amador-Noguez D; Department of Microbiology, University of Wisconsin-Madison, Madison, WI, USA., Simcox JA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA. jsimcox@wisc.edu.; Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, WI, USA. jsimcox@wisc.edu., Pagliarini DJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA. pagliarini@wustl.edu.; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Morgridge Institute for Research, Madison, WI, USA. pagliarini@wustl.edu.; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Sep; Vol. 32 (9), pp. 1622-1632. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1545-9985
DOI:10.1038/s41594-025-01596-4