Recombinant quadrivalent influenza vaccine (RIV) induces robust cell-mediated and HA-specific B cell humoral immune responses among healthcare personnel.

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Title: Recombinant quadrivalent influenza vaccine (RIV) induces robust cell-mediated and HA-specific B cell humoral immune responses among healthcare personnel.
Authors: Mishina M; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: vvn6@cdc.gov., Cao W; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Ende Z; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA; Oak Ridge Institute for Science and Education (ORISE), CDC Fellowship Program, Oak Ridge, TN, USA., Sharma SS; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Ray SD; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kumari R; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA; Department of Anesthesiology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA., Kumar A; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Shanmugasundaram U; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Bohannon CD; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA; Oak Ridge Institute for Science and Education (ORISE), CDC Fellowship Program, Oak Ridge, TN, USA., Ranjan P; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Chang J; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Carney P; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Stevens J; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Levine MZ; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kim S; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Wesley M; Abt Associates, 2200 Century Pkwy NE Ste 950, Atlanta, GA, USA., Ball S; Westat, 1600 Research Blvd, Rockville, MD, USA., Pando MJ; Baylor Scott & White Health, Baylor College of Medicine - Temple, and Texas A & M University College of Medicine, Temple, TX, USA., Dobin S; Baylor Scott & White Health, Baylor College of Medicine - Temple, and Texas A & M University College of Medicine, Temple, TX, USA., Knight PR; Department of Anesthesiology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA., Varadarajan R; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka, India., Thompson M; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Dawood FS; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Naleway AL; Kaiser Permanente Center for Health Research, Portland, OR, USA., Gaglani M; Baylor Scott & White Health, Baylor College of Medicine - Temple, and Texas A & M University College of Medicine, Temple, TX, USA., Gangappa S; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA., Sambhara S; Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: ssambhara@cdc.gov.
Source: Vaccine [Vaccine] 2025 Aug 13; Vol. 61, pp. 127361. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2518
DOI:10.1016/j.vaccine.2025.127361