Dopamine and cortical neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction.
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| Title: | Dopamine and cortical neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction. |
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| Authors: | Chedid J; The University of Sydney, Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Li Y; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The University of Sydney, Kolling Institute & Faculty of Medicine and Health Northern Clinical School, Sydney, NSW, Australia.; Neuroscience Research Australia, Sydney, NSW, Australia., Labrador-Garrido A; The University of Sydney, Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Abu-Bonsrah D; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Pavan C; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Fraser T; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Ovchinnikov D; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Zhong M; The University of Sydney, Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia., Davis R; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The University of Sydney, Kolling Institute & Faculty of Medicine and Health Northern Clinical School, Sydney, NSW, Australia., Strbenac D; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The University of Sydney, School of Mathematics and Statistics, Sydney, NSW, Australia., Johnston JA; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; NysnoBio, Mills Valley, CA, USA., Thompson LH; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Kirik D; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; NysnoBio, Mills Valley, CA, USA.; The University of Sydney, Charles Perkins Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia.; BRAINS Unit, BMC D11, Lund University, Lund, Sweden., Parish CL; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The Florey Institute of Neuroscience and Mental Health & The University of Melbourne, Parkville, VIC, Australia., Halliday GM; The University of Sydney, Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Sue CM; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; The University of Sydney, Kolling Institute & Faculty of Medicine and Health Northern Clinical School, Sydney, NSW, Australia.; Neuroscience Research Australia, Sydney, NSW, Australia., Wali G; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. g.wali@unsw.edu.au.; The University of Sydney, Kolling Institute & Faculty of Medicine and Health Northern Clinical School, Sydney, NSW, Australia. g.wali@unsw.edu.au.; Neuroscience Research Australia, Sydney, NSW, Australia. g.wali@unsw.edu.au., Dzamko N; The University of Sydney, Brain and Mind Centre & Faculty of Medicine and Health School of Medical Sciences, Sydney, NSW, Australia. nicolas.dzamko@sydney.edu.au.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. nicolas.dzamko@sydney.edu.au. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Jun 20; Vol. 11 (1), pp. 177. Date of Electronic Publication: 2025 Jun 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2373-8057 |
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| DOI: | 10.1038/s41531-025-01048-2 |
