Formation of seeding-competent α-synuclein aggregates in parkin-deficient iPSC-derived human neurons.
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| Title: | Formation of seeding-competent α-synuclein aggregates in parkin-deficient iPSC-derived human neurons. |
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| Authors: | Schmidt SI; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Okarmus J; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Madsen DA; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Hansen JS; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Gregersen E; DANDRITE, Danish Research Institute of Translational Neuroscience & Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Gram H; DANDRITE, Danish Research Institute of Translational Neuroscience & Department of Biomedicine, Aarhus University, Aarhus, Denmark., Winkelmann LS; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Oliveira AS; Department of Materials and Production, Faculty of Engineering and Science, Aalborg University, Aalborg, Denmark., Heon-Roberts R; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Ryan BJ; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Freude K; Faculty of Health and Medical Sciences, Department of Veterinary and Animal Sciences, Section for Pathobiological Sciences, University of Copenhagen, Copenhagen, Denmark., Blaabjerg M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; BRIDGE - Brain Research Inter-Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Jensen PH; DANDRITE, Danish Research Institute of Translational Neuroscience & Department of Biomedicine, Aarhus University, Aarhus, Denmark., Meyer M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. mmeyer@health.sdu.dk.; Department of Neurology, Odense University Hospital, Odense, Denmark. mmeyer@health.sdu.dk.; BRIDGE - Brain Research Inter-Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. mmeyer@health.sdu.dk. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Jun 21; Vol. 11 (1), pp. 180. Date of Electronic Publication: 2025 Jun 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2373-8057 |
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| DOI: | 10.1038/s41531-025-01038-4 |
