Is highly purified cannabidiol a treatment opportunity for drug-resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?
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| Title: | Is highly purified cannabidiol a treatment opportunity for drug-resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder? |
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| Authors: | Vignoli A; Childhood and Adolescence Neuropsychiatry Unit, Grande Ospedale Metropolitano Niguarda, Milan, Italy.; Health Sciences Department, Università degli Studi di Milano, Milan, Italy., Prato G; Unit of Child Neuropsychiatry, IRCCS Istituto Giannina Gaslini, Full Member of European Reference Network EpiCARE, Genoa, Italy., Alfei E; Pediatric Neurology Unit, Buzzi Children's Hospital, Milan, Italy., Bagnasco I; Division of Child Neuropsychiatry, Martini Hospital, Torino, Italy., Danieli A; Epilepsy Unit, IRCCS E. Medea Scientific Institute, Conegliano, Italy., Celario M; Department of Child Neurology and Psychiatry, IRCCS Mondino Foundation, Pavia, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy., Favaro J; Department of Women's and Child's Health, University of Padua, Padova, Italy.; Paediatric Neurology and Neurophysiology Unit - University Hospital of Padua, Padova, Italy., Matricardi S; Department of Pediatrics, University of Chieti, Chieti, Italy., Operto FF; Department of Science of Health School of Medicine, University Magna Greacia of Catanzaro, Catanzaro, Italy., Orsini A; Pediatric Neurology, University Hospital of Pisa, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy., Bernasconi DP; Bicocca Bioinformatics Biostatistics and Bioimaging Center, School of Medicine and Surgery, University of Milano-Bicocca, Italy.; Clinical Research and Innovation Unit, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Pietrafusa N; Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital IRCCS, Full Member of European Reference Network EpiCARE, Rome, Italy., Ricci E; Health Sciences Department, Università degli Studi di Milano, Milan, Italy.; Child Neurology Unit, Epilepsy Center, San Paolo Hospital, Member of European Reference Network EpiCARE, Milan, Italy., Manfredini L; Paediatric Chronic Pain and Palliative Care Service, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Balletto G; Unit of Child Neuropsychiatry, IRCCS Istituto Giannina Gaslini, Full Member of European Reference Network EpiCARE, Genoa, Italy., Bonanni P; Epilepsy Unit, IRCCS E. Medea Scientific Institute, Conegliano, Italy., Canevini MP; Health Sciences Department, Università degli Studi di Milano, Milan, Italy.; Child Neurology Unit, Epilepsy Center, San Paolo Hospital, Member of European Reference Network EpiCARE, Milan, Italy., De Giorgis V; Department of Child Neurology and Psychiatry, IRCCS Mondino Foundation, Pavia, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy., Nobili L; Unit of Child Neuropsychiatry, IRCCS Istituto Giannina Gaslini, Full Member of European Reference Network EpiCARE, Genoa, Italy., Sartori S; Department of Women's and Child's Health, University of Padua, Padova, Italy.; Paediatric Neurology and Neurophysiology Unit - University Hospital of Padua, Padova, Italy., Savini MN; Child Neurology Unit, Epilepsy Center, San Paolo Hospital, Member of European Reference Network EpiCARE, Milan, Italy., Viganò I; Child Neurology Unit, Epilepsy Center, San Paolo Hospital, Member of European Reference Network EpiCARE, Milan, Italy., Specchio N; Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital IRCCS, Full Member of European Reference Network EpiCARE, Rome, Italy.; University Hospitals KU Leuven, Leuven, Belgium. |
| Source: | Epilepsia open [Epilepsia Open] 2025 Aug; Vol. 10 (4), pp. 1111-1119. Date of Electronic Publication: 2025 Jun 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101692036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9239 (Electronic) Linking ISSN: 24709239 NLM ISO Abbreviation: Epilepsia Open Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9239 |
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| DOI: | 10.1002/epi4.70078 |
