A first-in-human study of NXT007, a next-generation, activated factor VIII-mimetic bispecific antibody, in healthy participants.
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| Title: | A first-in-human study of NXT007, a next-generation, activated factor VIII-mimetic bispecific antibody, in healthy participants. |
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| Authors: | Sambe T; Clinical Research Center for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo, Japan; Department of Clinical Pharmacology, Graduate School of Medicine, Showa Medical University, Tokyo, Japan., Miwa T; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Yoneyama K; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Ishida T; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Yamazaki T; Clinical Research Center for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo, Japan., Shima M; Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Japan. Electronic address: mshima@naramed-u.ac.jp. |
| Source: | Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2025 Oct; Vol. 23 (10), pp. 3098-3110. Date of Electronic Publication: 2025 Jun 17. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1538-7836 |
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| DOI: | 10.1016/j.jtha.2025.06.013 |
