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Immune regulation of TLR4/MYD88/ NF-κB/AP1/IL-6 pathway and modulation of aldosterone/PPARα receptors by eplerenone and fenofibrate in ovarian ischemia reperfusion induced injury.

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Title: Immune regulation of TLR4/MYD88/ NF-κB/AP1/IL-6 pathway and modulation of aldosterone/PPARα receptors by eplerenone and fenofibrate in ovarian ischemia reperfusion induced injury.
Authors: Refaie MMM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt. Electronic address: marwamonier@mu.edu.eg., Abdel-Hakeem EA; Department of Medical Physiology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt., Shehata S; Department of Cardiology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt., Elsaghir SMM; Department of Internal medicine, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt., Mokhemer SA; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt, and Faculty of Oral and Dental Medicine, Lotus University, 61768, El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt. Electronic address: Sahar.ahmedmokhemer@lum.edu.eg., Ahmed NZM; Department of Medical Biochemistry, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Department of Biochemistry, Faculty of Medicine, Al-Baha University, Albaha 65525, Saudi Arabia., Elsayed SH; Department of Medical Biochemistry, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt., Mageed AAAA; Department of Physiology, Faculty of Medicine, Cairo University, 12613, Giza, Egypt., Mohamed HR; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt., Shawky HA; Department of Anatomy and Embryology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt., Ali DME; Department of Biochemistry and Molecular Biology, Faculty of pharmacy, Sohag university, 82524, Sohag, Egypt.
Source: International immunopharmacology [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115113. Date of Electronic Publication: 2025 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
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  Data: Immune regulation of TLR4/MYD88/ NF-κB/AP1/IL-6 pathway and modulation of aldosterone/PPARα receptors by eplerenone and fenofibrate in ovarian ischemia reperfusion induced injury.
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  Data: <searchLink fieldCode="AU" term="%22Refaie+MMM%22">Refaie MMM</searchLink>; Department of Medical Pharmacology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt. Electronic address: marwamonier@mu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Abdel-Hakeem+EA%22">Abdel-Hakeem EA</searchLink>; Department of Medical Physiology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Shehata+S%22">Shehata S</searchLink>; Department of Cardiology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Elsaghir+SMM%22">Elsaghir SMM</searchLink>; Department of Internal medicine, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Mokhemer+SA%22">Mokhemer SA</searchLink>; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, 61511, El-Minia, Egypt, and Faculty of Oral and Dental Medicine, Lotus University, 61768, El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt. Electronic address: Sahar.ahmedmokhemer@lum.edu.eg.<br /><searchLink fieldCode="AU" term="%22Ahmed+NZM%22">Ahmed NZM</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Department of Biochemistry, Faculty of Medicine, Al-Baha University, Albaha 65525, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Elsayed+SH%22">Elsayed SH</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Mageed+AAAA%22">Mageed AAAA</searchLink>; Department of Physiology, Faculty of Medicine, Cairo University, 12613, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohamed+HR%22">Mohamed HR</searchLink>; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Shawky+HA%22">Shawky HA</searchLink>; Department of Anatomy and Embryology, Faculty of Medicine, Minia University, 61511 El-Minia, Egypt; Faculty of Medicine, Minia National University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Ali+DME%22">Ali DME</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of pharmacy, Sohag university, 82524, Sohag, Egypt.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115113. <i>Date of Electronic Publication: </i>2025 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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