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Dissecting the role of SPRY4-IT1 and TUG1 in modulating miR-425/TGF-β/ Smad signaling in mediating renal fibrosis and inflammation in lupus nephritis: Novel biomarkers and therapeutic targets.

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Title: Dissecting the role of SPRY4-IT1 and TUG1 in modulating miR-425/TGF-β/ Smad signaling in mediating renal fibrosis and inflammation in lupus nephritis: Novel biomarkers and therapeutic targets.
Authors: Abd-Elmawla MA; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. Electronic address: mei.abdelmawla@pharma.cu.edu.eg., Zidan M; Internal Medicine Department (Nephrology Unit), Faculty of Medicine, Cairo University, Cairo, Egypt., Elsabagh YA; Internal Medicine Department (Rheumatology and Clinical Immunology Unit), Faculty of Medicine, Cairo University, Cairo, Egypt., Elfar N; Biochemistry Department, School of Health and Social work, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, 11578 Cairo, Egypt; Egyptian Drug Authority (EDA), Ministry of Health and Population, Cairo 11567, Egypt., Radwan AF; Collage of Pharmacy, University of Kut, Wasit, 52001, Iraq; Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Source: International immunopharmacology [Int Immunopharmacol] 2025 Sep 23; Vol. 162, pp. 115132. Date of Electronic Publication: 2025 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Abd-Elmawla+MA%22">Abd-Elmawla MA</searchLink>; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. Electronic address: mei.abdelmawla@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Zidan+M%22">Zidan M</searchLink>; Internal Medicine Department (Nephrology Unit), Faculty of Medicine, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Elsabagh+YA%22">Elsabagh YA</searchLink>; Internal Medicine Department (Rheumatology and Clinical Immunology Unit), Faculty of Medicine, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Elfar+N%22">Elfar N</searchLink>; Biochemistry Department, School of Health and Social work, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, 11578 Cairo, Egypt; Egyptian Drug Authority (EDA), Ministry of Health and Population, Cairo 11567, Egypt.<br /><searchLink fieldCode="AU" term="%22Radwan+AF%22">Radwan AF</searchLink>; Collage of Pharmacy, University of Kut, Wasit, 52001, Iraq; Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
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