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FOXC1 Expression Predicts Capecitabine Efficacy in Patients with Triple-Negative Breast Cancer from the GEICAM_CIBOMA Trial.

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Title: FOXC1 Expression Predicts Capecitabine Efficacy in Patients with Triple-Negative Breast Cancer from the GEICAM_CIBOMA Trial.
Authors: Rojo F; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Department of Pathology, Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS-FJD, UAM)-CIBERONC, Madrid, Spain., Taylor CR; Onconostic Technologies, Inc. (OT), Evanston, Illinois., Barrios C; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Centro de Pesquisa Clinica Hospital São Lucas da PUCRS, Porto Alegre, Brazil., Torrecillas L; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Centro Medico Nacional 20 de Noviembre ISSSTE, CDMX, Porto Alegre, Mexico., Ruiz-Borrego M; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Universitario Virgen del Rocio, Sevilla, Spain., Perez-Buira S; Department of Pathology, Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS-FJD, UAM)-CIBERONC, Madrid, Spain., Bines J; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; National Cancer Institute (INCA), Brazil., Guerrero-Zotano A; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Instituto Valenciano de Oncologia (IVO), Valencia, Spain., Garcia-Saenz JA; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Department of Oncology and Instituto de Investigacion Sanitaria Hospital Clinico San Carlos (IdISSC), Madrid, Spain., Torres R; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Instituto Nacional del Cancer, Santiago, Chile., de la Haba-Rodriguez J; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Instituto Maimonides de Investigacion Biomedica de Cordoba (IMIBIC)-Hospital Universitario Reina Sofia, Universidad de Cordoba, Cordoba, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain., Ayala F; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital General Universitario Morales Meseguer, Murcia, Spain.; Department of Medical Oncology, Hospital General Universitario Gregorio Marañon Instituto de Investigacion Sanitaria Gregorio Marañon, Madrid, Spain., Gomez H; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Peru.; Universidad Ricardo Palma, Lima, Peru., Llombart A; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Arnau de Vilanova, Valencia, Spain., Rodriguez de la Borbolla M; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital de Valme, Sevilla, Spain., Baena-Cañada JM; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Universitario Puerta del Mar, Instituto de Investigacion e Innovacion Biomedica de Cadiz (INIBICA), Cadiz, Spain., Barnadas A; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Calvo L; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain., Herranz J; GEICAM, Spanish Breast Cancer Group, Madrid, Spain., Rincon R; GEICAM, Spanish Breast Cancer Group, Madrid, Spain., Caballero R; GEICAM, Spanish Breast Cancer Group, Madrid, Spain., Bermejo B; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain.; Medicine Department, Hospital Clinico Universitario de Valencia, Instituto de Investigacion Sanitaria (INCLIVA), Universidad de Valencia, Valencia, Spain., Ray PS; Onconostic Technologies, Inc. (OT), Evanston, Illinois., Martin M; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain.; Department of Medical Oncology, Hospital General Universitario Gregorio Marañon Instituto de Investigacion Sanitaria Gregorio Marañon, Madrid, Spain.; Universidad Complutense, Madrid, Spain.
Corporate Authors: GEICAM_CIBOMA Clinical Trial Group
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Sep 02; Vol. 31 (17), pp. 3715-3724.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FOXC1 Expression Predicts Capecitabine Efficacy in Patients with Triple-Negative Breast Cancer from the GEICAM_CIBOMA Trial.
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  Data: <searchLink fieldCode="AU" term="%22Rojo+F%22">Rojo F</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Department of Pathology, Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS-FJD, UAM)-CIBERONC, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Taylor+CR%22">Taylor CR</searchLink>; Onconostic Technologies, Inc. (OT), Evanston, Illinois.<br /><searchLink fieldCode="AU" term="%22Barrios+C%22">Barrios C</searchLink>; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Centro de Pesquisa Clinica Hospital São Lucas da PUCRS, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Torrecillas+L%22">Torrecillas L</searchLink>; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Centro Medico Nacional 20 de Noviembre ISSSTE, CDMX, Porto Alegre, Mexico.<br /><searchLink fieldCode="AU" term="%22Ruiz-Borrego+M%22">Ruiz-Borrego M</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Universitario Virgen del Rocio, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Buira+S%22">Perez-Buira S</searchLink>; Department of Pathology, Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS-FJD, UAM)-CIBERONC, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bines+J%22">Bines J</searchLink>; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; National Cancer Institute (INCA), Brazil.<br /><searchLink fieldCode="AU" term="%22Guerrero-Zotano+A%22">Guerrero-Zotano A</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Instituto Valenciano de Oncologia (IVO), Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Saenz+JA%22">Garcia-Saenz JA</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Department of Oncology and Instituto de Investigacion Sanitaria Hospital Clinico San Carlos (IdISSC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Torres+R%22">Torres R</searchLink>; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Instituto Nacional del Cancer, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22de+la+Haba-Rodriguez+J%22">de la Haba-Rodriguez J</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Instituto Maimonides de Investigacion Biomedica de Cordoba (IMIBIC)-Hospital Universitario Reina Sofia, Universidad de Cordoba, Cordoba, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ayala+F%22">Ayala F</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital General Universitario Morales Meseguer, Murcia, Spain.; Department of Medical Oncology, Hospital General Universitario Gregorio Marañon Instituto de Investigacion Sanitaria Gregorio Marañon, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gomez+H%22">Gomez H</searchLink>; LACOG, Latin American Cooperative Oncology Group, Porto Alegre, Brazil.; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Peru.; Universidad Ricardo Palma, Lima, Peru.<br /><searchLink fieldCode="AU" term="%22Llombart+A%22">Llombart A</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Arnau de Vilanova, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez+de+la+Borbolla+M%22">Rodriguez de la Borbolla M</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital de Valme, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Baena-Cañada+JM%22">Baena-Cañada JM</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital Universitario Puerta del Mar, Instituto de Investigacion e Innovacion Biomedica de Cadiz (INIBICA), Cadiz, Spain.<br /><searchLink fieldCode="AU" term="%22Barnadas+A%22">Barnadas A</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo+L%22">Calvo L</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Herranz+J%22">Herranz J</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rincon+R%22">Rincon R</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Caballero+R%22">Caballero R</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bermejo+B%22">Bermejo B</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain.; Medicine Department, Hospital Clinico Universitario de Valencia, Instituto de Investigacion Sanitaria (INCLIVA), Universidad de Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Ray+PS%22">Ray PS</searchLink>; Onconostic Technologies, Inc. (OT), Evanston, Illinois.<br /><searchLink fieldCode="AU" term="%22Martin+M%22">Martin M</searchLink>; GEICAM, Spanish Breast Cancer Group, Madrid, Spain.; Oncology Biomedical Research National Network (CIBERONC-ISCIII), Madrid, Spain.; Department of Medical Oncology, Hospital General Universitario Gregorio Marañon Instituto de Investigacion Sanitaria Gregorio Marañon, Madrid, Spain.; Universidad Complutense, Madrid, Spain.
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  Data: <searchLink fieldCode="CA" term="%22GEICAM%26#95%3BCIBOMA+Clinical+Trial+Group%22">GEICAM_CIBOMA Clinical Trial Group</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Sep 02; Vol. 31 (17), pp. 3715-3724.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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