Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition.
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| Title: | Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition. |
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| Authors: | Break MKB; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia; Medical and Diagnostic Research Centre, University of Ha'il, Ha'il, 55473, Saudi Arabia. Electronic address: m.binbreak@uoh.edu.sa., Hussein W; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Alafnan D; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Almutairi HO; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Katamesh AA; Department of Pharmaceutics, College of Pharmacy, University of Ha'il, Ha'il, 81442, Saudi Arabia., Alshammari MD; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia. |
| Source: | Journal of ethnopharmacology [J Ethnopharmacol] 2025 Aug 29; Vol. 352, pp. 120201. Date of Electronic Publication: 2025 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1872-7573 |
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| DOI: | 10.1016/j.jep.2025.120201 |
