Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition.
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| Title: | Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition. |
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| Authors: | Break MKB; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia; Medical and Diagnostic Research Centre, University of Ha'il, Ha'il, 55473, Saudi Arabia. Electronic address: m.binbreak@uoh.edu.sa., Hussein W; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Alafnan D; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Almutairi HO; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia., Katamesh AA; Department of Pharmaceutics, College of Pharmacy, University of Ha'il, Ha'il, 81442, Saudi Arabia., Alshammari MD; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia. |
| Source: | Journal of ethnopharmacology [J Ethnopharmacol] 2025 Aug 29; Vol. 352, pp. 120201. Date of Electronic Publication: 2025 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40571228 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Break+MKB%22">Break MKB</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia; Medical and Diagnostic Research Centre, University of Ha'il, Ha'il, 55473, Saudi Arabia. Electronic address: m.binbreak@uoh.edu.sa.<br /><searchLink fieldCode="AU" term="%22Hussein+W%22">Hussein W</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alafnan+D%22">Alafnan D</searchLink>; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almutairi+HO%22">Almutairi HO</searchLink>; College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Katamesh+AA%22">Katamesh AA</searchLink>; Department of Pharmaceutics, College of Pharmacy, University of Ha'il, Ha'il, 81442, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alshammari+MD%22">Alshammari MD</searchLink>; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha'il, Ha'il, Saudi Arabia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227903310%22">Journal of ethnopharmacology</searchLink> [J Ethnopharmacol] 2025 Aug 29; Vol. 352, pp. 120201. <i>Date of Electronic Publication: </i>2025 Jun 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Sequoia%22">Elsevier Sequoia </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7903310 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7573 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203788741%22">03788741 </searchLink><i>NLM ISO Abbreviation: </i>J Ethnopharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40571228 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jep.2025.120201 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 120201 Titles: – TitleFull: Achillea fragrantissima (Forssk.) Sch. Bip. essential oil inhibits the growth of pancreatic cancer cells via induction of necrosis, sub-G1 arrest, modulation of β-catenin/ERK signalling pathways and p38α MAPK, CDK2, EGFR inhibition. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Break MKB – PersonEntity: Name: NameFull: Hussein W – PersonEntity: Name: NameFull: Alafnan D – PersonEntity: Name: NameFull: Almutairi HO – PersonEntity: Name: NameFull: Katamesh AA – PersonEntity: Name: NameFull: Alshammari MD IsPartOfRelationships: – BibEntity: Dates: – D: 29 M: 08 Text: 2025 Aug 29 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1872-7573 Numbering: – Type: volume Value: 352 Titles: – TitleFull: Journal of ethnopharmacology Type: main |
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