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Condensate Formation of the Human RNA-binding Protein SMAUG1 is Controlled by its Intrinsically Disordered Regions and Interactions with 14-3-3 Proteins.

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Title: Condensate Formation of the Human RNA-binding Protein SMAUG1 is Controlled by its Intrinsically Disordered Regions and Interactions with 14-3-3 Proteins.
Authors: Carey O; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: 117348426@umail.ucc.ie., Fehilly J; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: john.fehilly@ucdconnect.ie., O'Leary ET; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: eoghan.oleary@targovax.com., O'Shea S; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: 117458944@umail.ucc.ie., Juda K; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: klaudia.juda@msd.com., Fitzel R; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: rahel_fitzel@yahoo.de., Selvaraj P; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: poojaselvaraj.au@gmail.com., Burk K; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: Kburk@ucc.ie., Lindsay AJ; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: a.lindsay@ucc.ie., Young P; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: p.young@ucc.ie., Pancsa R; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest 1117, Hungary. Electronic address: pancsa.rita@ttk.hu., Mészáros B; St Jude Children's Research Hospital, 262 Danny Thomas Place, 38105 Memphis, TN, USA. Electronic address: balint.meszaros@stjude.org., Dean K; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: k.dean@ucc.ie.
Source: Journal of molecular biology [J Mol Biol] 2025 Oct 01; Vol. 437 (19), pp. 169314. Date of Electronic Publication: 2025 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE
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  Data: Condensate Formation of the Human RNA-binding Protein SMAUG1 is Controlled by its Intrinsically Disordered Regions and Interactions with 14-3-3 Proteins.
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  Data: <searchLink fieldCode="AU" term="%22Carey+O%22">Carey O</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: 117348426@umail.ucc.ie.<br /><searchLink fieldCode="AU" term="%22Fehilly+J%22">Fehilly J</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: john.fehilly@ucdconnect.ie.<br /><searchLink fieldCode="AU" term="%22O'Leary+ET%22">O'Leary ET</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: eoghan.oleary@targovax.com.<br /><searchLink fieldCode="AU" term="%22O'Shea+S%22">O'Shea S</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: 117458944@umail.ucc.ie.<br /><searchLink fieldCode="AU" term="%22Juda+K%22">Juda K</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: klaudia.juda@msd.com.<br /><searchLink fieldCode="AU" term="%22Fitzel+R%22">Fitzel R</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: rahel_fitzel@yahoo.de.<br /><searchLink fieldCode="AU" term="%22Selvaraj+P%22">Selvaraj P</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: poojaselvaraj.au@gmail.com.<br /><searchLink fieldCode="AU" term="%22Burk+K%22">Burk K</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: Kburk@ucc.ie.<br /><searchLink fieldCode="AU" term="%22Lindsay+AJ%22">Lindsay AJ</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: a.lindsay@ucc.ie.<br /><searchLink fieldCode="AU" term="%22Young+P%22">Young P</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: p.young@ucc.ie.<br /><searchLink fieldCode="AU" term="%22Pancsa+R%22">Pancsa R</searchLink>; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest 1117, Hungary. Electronic address: pancsa.rita@ttk.hu.<br /><searchLink fieldCode="AU" term="%22Mészáros+B%22">Mészáros B</searchLink>; St Jude Children's Research Hospital, 262 Danny Thomas Place, 38105 Memphis, TN, USA. Electronic address: balint.meszaros@stjude.org.<br /><searchLink fieldCode="AU" term="%22Dean+K%22">Dean K</searchLink>; School of Biochemistry and Cell Biology, University College Cork, Cork T12 XF62, Ireland. Electronic address: k.dean@ucc.ie.
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