Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut.
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| Title: | Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut. |
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| Authors: | Li C; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Adamson C; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Ng AWR; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Liang Y; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Hong Z; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673, Singapore., Loh JT; School of Biological Sciences (SBS), Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore., Ng SK; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore.; Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore., Kwan JMC; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore., Feng S; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Ng EWL; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore., Nair S; School of Biological Sciences (SBS), Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore., Ruedl C; School of Biological Sciences (SBS), Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore., Wong SH; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore.; Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore., Lam KP; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Singapore, 138648, Singapore., Qiao Y; School of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore. yuan.qiao@ntu.edu.sg. |
| Source: | Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5577. Date of Electronic Publication: 2025 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-60678-5 |
