Radiation therapy results in preferential tumor antigen-specific lymphodepletion in head and neck cancer.
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| Title: | Radiation therapy results in preferential tumor antigen-specific lymphodepletion in head and neck cancer. |
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| Authors: | Zenga J; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA. jyzenga@mcw.edu.; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA. jyzenga@mcw.edu.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA. jyzenga@mcw.edu., Awan MJ; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Frei A; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Foeckler J; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Kuehn R; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Kasprzak J; Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA., Massey B; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Bruening J; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Akakpo K; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Shukla M; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Wong SJ; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Mathison AJ; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, USA., Wendt Andrae J; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Hunt B; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA., Puzyrenko A; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA., Jin VX; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.; Division of Biostatistics, Data Science Institute, Medical College of Wisconsin, Milwaukee, WI, USA., Memon AA; Medical College of Wisconsin, Milwaukee, WI, USA., Villarreal Espinosa O; Medical College of Wisconsin, Milwaukee, WI, USA., Chen F; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Shaheduzzaman M; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Kearl T; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Hematti P; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Himburg HA; Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, WI, USA. hhimburg@mcw.edu.; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WIh, USA. hhimburg@mcw.edu.; Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA. hhimburg@mcw.edu. |
| Source: | Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5660. Date of Electronic Publication: 2025 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-60827-w |
