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MORC2 is a phosphorylation-dependent DNA compaction machine.

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Title: MORC2 is a phosphorylation-dependent DNA compaction machine.
Authors: Tan W; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Park J; Department of Physics and Astronomy, Seoul National University, Seoul, Republic of Korea., Venugopal H; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3168, Australia., Lou J; Department of Biochemistry and Pharmacology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Dias PS; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX, 75080, USA., Baldoni PL; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Moon KW; Department of Physics and Astronomy, Seoul National University, Seoul, Republic of Korea., Dite TA; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Keenan CR; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Gurzau AD; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Lee J; Department of Physics and Astronomy, Seoul National University, Seoul, Republic of Korea., Johanson TM; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Leis A; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Yousef J; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Vaibhav V; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Dagley LF; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Ang CS; The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC 3052, Australia., Corso LD; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Davidovich C; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3168, Australia., Vervoort SJ; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Smyth GK; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; School of Mathematics and Statistics, The University of Melbourne, Melbourne, VIC 3010, Australia., Blewitt ME; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Allan RS; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia., Hinde E; Department of Biochemistry and Pharmacology, The University of Melbourne, Melbourne, VIC, 3052, Australia., D'Arcy S; Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX, 75080, USA., Ryu JK; Department of Physics and Astronomy, Seoul National University, Seoul, Republic of Korea. prof.love@snu.ac.kr., Shakeel S; WEHI, 1G Royal Parade, Parkville, VIC, 3052, Australia. shakeel.s@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3052, Australia. shakeel.s@wehi.edu.au.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia. shakeel.s@wehi.edu.au.; Department of Biochemistry and Pharmacology, The University of Melbourne, Melbourne, VIC, 3052, Australia. shakeel.s@wehi.edu.au.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5606. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60751-z