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Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity.

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Title: Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity.
Authors: Liu T; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Zhang M; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Farsh T; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Li H; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Kishishita A; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA., Barpanda A; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, 94158, USA., Leung SG; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Zhu J; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Jung H; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, 94158, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA., Hua JT; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Zhu X; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA., Kim AB; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, 63108, USA.; Bursky Center for Human Immunology and Immunotherapy, Washington University School of Medicine, St. Louis, MO, 63110, USA., Goo YA; Mass Spectrometry Technology Access Center at McDonnell Genome Institute (MTAC@MGI) at Washington University School of Medicine, St. Louis, MO, 63108, USA., Son M; Mass Spectrometry Technology Access Center at McDonnell Genome Institute (MTAC@MGI) at Washington University School of Medicine, St. Louis, MO, 63108, USA., Kim J; Mass Spectrometry Technology Access Center at McDonnell Genome Institute (MTAC@MGI) at Washington University School of Medicine, St. Louis, MO, 63108, USA., Subramanian A; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA., Sjöström M; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Clinical Sciences, Division of Oncology, Lund University, Lund, Sweden.; Division of Haematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden., Fuh KC; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Division of gynecologic oncology, University of California, San Francisco, CA, 94158, USA., Chapman JS; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Division of gynecologic oncology, University of California, San Francisco, CA, 94158, USA., Carnevale J; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, 94158, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA, 94129, USA., Gilbert LA; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, CA, 94158, USA.; Arc Institute, Palo Alto, CA, 94304, USA., Lakkaraju A; Pharmaceutical Sciences and Pharmacogenomics, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Ophthalmology, University of California San Francisco, San Francisco, CA, 94115, USA., Bruno PM; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, CA, 94158, USA., Quigley D; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, CA, 94158, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 94158, USA., Wiita AP; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, 94143, USA.; Chan Zuckerberg Biohub San Francisco, San Francisco, CA, 94158, USA., Feng FY; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, CA, 94158, USA., DeSelm CJ; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, 63108, USA. deselmc@wustl.edu.; Bursky Center for Human Immunology and Immunotherapy, Washington University School of Medicine, St. Louis, MO, 63110, USA. deselmc@wustl.edu.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5616. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60745-x