MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling.
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| Title: | MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling. |
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| Authors: | Kim S; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Han HJ; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Han J; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Choi Y; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Ryoo IJ; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Sivaraman A; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea., Lee K; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea., Kim BY; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Moon EY; Department of Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Soung NK; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea. soungnak@kribb.re.kr.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea. soungnak@kribb.re.kr. |
| Source: | Scientific reports [Sci Rep] 2025 Jul 01; Vol. 15 (1), pp. 21781. Date of Electronic Publication: 2025 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-05203-w |
