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MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling.

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Title: MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling.
Authors: Kim S; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Han HJ; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Han J; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Choi Y; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea., Ryoo IJ; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Sivaraman A; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea., Lee K; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea., Kim BY; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea., Moon EY; Department of Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea., Soung NK; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea. soungnak@kribb.re.kr.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea. soungnak@kribb.re.kr.
Source: Scientific reports [Sci Rep] 2025 Jul 01; Vol. 15 (1), pp. 21781. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling.
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  Data: <searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+HJ%22">Han HJ</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+Y%22">Choi Y</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryoo+IJ%22">Ryoo IJ</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sivaraman+A%22">Sivaraman A</searchLink>; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+K%22">Lee K</searchLink>; College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BY%22">Kim BY</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+EY%22">Moon EY</searchLink>; Department of Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Soung+NK%22">Soung NK</searchLink>; Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea. soungnak@kribb.re.kr.; Department of Biomolecular Science, Korea National University of Science and Technology, Daejeon, 34113, Republic of Korea. soungnak@kribb.re.kr.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Jul 01; Vol. 15 (1), pp. 21781. <i>Date of Electronic Publication: </i>2025 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40595789
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        Value: 10.1038/s41598-025-05203-w
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      – TitleFull: MO-2097 inhibits EMT and angiogenesis in colorectal cancer by targeting RAF/MEK/ERK signaling.
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            – D: 01
              M: 07
              Text: 2025 Jul 01
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