Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response.

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Title: Engineering the bone metastatic prostate cancer niche through a microphysiological system to report patient-specific treatment response.
Authors: Sánchez-de-Diego C; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA., Yada RC; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA.; Department of Cellular and Molecular Biology, University of Wisconsin, Madison, WI, USA., Sethakorn N; Department of Medicine, Loyola University Chicago, Chicago, IL, USA.; Department of Cancer Biology, Loyola University Chicago, Chicago, IL, USA., Geiger PG; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA., Ding AB; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA., Heninger E; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA., Ahmed F; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA., Virumbrales-Muñoz M; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI, USA., Lupsa N; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA., Bartels E; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA., Stewart K; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA., Ponik SM; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI, USA., Sharifi MN; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Medicine, University of Wisconsin, Madison, WI, USA., Lang JM; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. jmlang@medicine.wisc.edu.; Department of Medicine, University of Wisconsin, Madison, WI, USA. jmlang@medicine.wisc.edu., Beebe DJ; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu., Kerr SC; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. skerr2@wisc.edu.
Source: Communications biology [Commun Biol] 2025 Jul 01; Vol. 8 (1), pp. 961. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sánchez-de-Diego+C%22">Sánchez-de-Diego C</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Yada+RC%22">Yada RC</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA.; Department of Cellular and Molecular Biology, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sethakorn+N%22">Sethakorn N</searchLink>; Department of Medicine, Loyola University Chicago, Chicago, IL, USA.; Department of Cancer Biology, Loyola University Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Geiger+PG%22">Geiger PG</searchLink>; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ding+AB%22">Ding AB</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Heninger+E%22">Heninger E</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ahmed+F%22">Ahmed F</searchLink>; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Virumbrales-Muñoz+M%22">Virumbrales-Muñoz M</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Lupsa+N%22">Lupsa N</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Bartels+E%22">Bartels E</searchLink>; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+K%22">Stewart K</searchLink>; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ponik+SM%22">Ponik SM</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sharifi+MN%22">Sharifi MN</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.; Department of Medicine, University of Wisconsin, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Lang+JM%22">Lang JM</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. jmlang@medicine.wisc.edu.; Department of Medicine, University of Wisconsin, Madison, WI, USA. jmlang@medicine.wisc.edu.<br /><searchLink fieldCode="AU" term="%22Beebe+DJ%22">Beebe DJ</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu.; Department of Pathology & Laboratory Medicine, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA. djbeebe@wisc.edu.<br /><searchLink fieldCode="AU" term="%22Kerr+SC%22">Kerr SC</searchLink>; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. skerr2@wisc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2025 Jul 01; Vol. 8 (1), pp. 961. <i>Date of Electronic Publication: </i>2025 Jul 01.
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