Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.

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Title: Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.
Authors: Krick KE; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Weekman EM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: eweekman@iu.edu., Johnson SN; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Sudduth TL; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Rogers CB; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Nicolayson EJ; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Kleinhenz MT; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Wilcock DM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: dwilcock@iu.edu.
Source: Neurobiology of disease [Neurobiol Dis] 2025 Sep; Vol. 213, pp. 107013. Date of Electronic Publication: 2025 Jun 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-953X
DOI:10.1016/j.nbd.2025.107013