Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease.
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| Title: | Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease. |
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| Authors: | Afrin H; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Robichaud JH; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Qamar U; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Harris PC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States., Gupta N; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States. |
| Source: | American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Aug 01; Vol. 329 (2), pp. F257-F268. Date of Electronic Publication: 2025 Jul 02. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1466 |
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| DOI: | 10.1152/ajprenal.00056.2025 |
