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Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease.

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Title: Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease.
Authors: Afrin H; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Robichaud JH; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Qamar U; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States., Harris PC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States., Gupta N; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Aug 01; Vol. 329 (2), pp. F257-F268. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease.
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  Data: <searchLink fieldCode="AU" term="%22Afrin+H%22">Afrin H</searchLink>; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.<br /><searchLink fieldCode="AU" term="%22Robichaud+JH%22">Robichaud JH</searchLink>; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.<br /><searchLink fieldCode="AU" term="%22Qamar+U%22">Qamar U</searchLink>; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.<br /><searchLink fieldCode="AU" term="%22Harris+PC%22">Harris PC</searchLink>; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States.<br /><searchLink fieldCode="AU" term="%22Gupta+N%22">Gupta N</searchLink>; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States.
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  Data: <searchLink fieldCode="JN" term="%22100901990%22">American journal of physiology. Renal physiology</searchLink> [Am J Physiol Renal Physiol] 2025 Aug 01; Vol. 329 (2), pp. F257-F268. <i>Date of Electronic Publication: </i>2025 Jul 02.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Physiological+Society%22">American Physiological Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100901990 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-1466 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215221466%22">15221466 </searchLink><i>NLM ISO Abbreviation: </i>Am J Physiol Renal Physiol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1152/ajprenal.00056.2025
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      – Code: eng
        Text: English
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      – TitleFull: Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease.
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            NameFull: Afrin H
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            – D: 01
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              Text: 2025 Aug 01
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            – TitleFull: American journal of physiology. Renal physiology
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