Colorectal cancer-infiltrating NK cell landscape analysis unravels tissue-resident PD-1+ NK cells in microsatellite instability tumors.

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Title: Colorectal cancer-infiltrating NK cell landscape analysis unravels tissue-resident PD-1+ NK cells in microsatellite instability tumors.
Authors: Obino V; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Giordano C; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Carlomagno S; Department of Medicine (DMED), University of Udine, Udine, Italy., Setti C; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Greppi M; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Bozzo M; Department of Earth, Environmental and Life Sciences (DISTAV), University of Genoa, Genoa, Italy., Pesce S; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Direzione Scientifica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Ferretti E; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; U.O. Medicina di Laboratorio, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Candiani S; Department of Earth, Environmental and Life Sciences (DISTAV), University of Genoa, Genoa, Italy.; Direzione Scientifica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Muccio L; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Ciferri E; Department of Abdominal Surgery - General and Hepatobiliopancreatic Surgery Unit, E.O. Ospedali Galliera, Genoa, Italy., Buttiron Webber T; Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy., Solari A; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy., Ortolani F; Department of Medicine (DMED), University of Udine, Udine, Italy., Paleari L; ALiSa, Liguria Health Authority, Genoa, Italy., Clavarezza M; Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy., Barberis A; Department of Abdominal Surgery - General and Hepatobiliopancreatic Surgery Unit, E.O. Ospedali Galliera, Genoa, Italy., Filauro M; Department of Abdominal Surgery - General and Hepatobiliopancreatic Surgery Unit, E.O. Ospedali Galliera, Genoa, Italy., Provinciali N; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy., Rutigliani M; Department of Laboratory and Service - Histological and Anatomical Pathology Unit, E.O. Ospedali Galliera, Genoa, Italy., Marcenaro E; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Direzione Scientifica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., DeCensi A; Division of Medical Oncology, E.O. Ospedali Galliera, Genoa, Italy.; Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom., Della Chiesa M; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Direzione Scientifica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Sivori S; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Direzione Scientifica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Source: Frontiers in immunology [Front Immunol] 2025 Jun 18; Vol. 16, pp. 1578444. Date of Electronic Publication: 2025 Jun 18 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1578444