Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.

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Title: Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.
Authors: Yang CC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Yeh JN; Institute of Nephrology and Blood Purification, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.; Department of Cardiology, The First Affiliated Hospital, Jinan University, Guangzhou, China., Hsu TW; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Chiang JY; Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan., Cheng BC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Sung PH; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net., Wu SC; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Post-Baccalaureate Program in Nursing, Asia University, Taichung, Taiwan., Huang CR; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Shao PL; Department of Nursing, Asia University Taichung, Taiwan. m8951016@gmail.com., Yip HK; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net.; Department of Medical Research, China Medical University Hospital, China Medical University, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Source: Histology and histopathology [Histol Histopathol] 2026 Feb; Vol. 41 (2), pp. 319-337. Date of Electronic Publication: 2025 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Histology and Histopathology Country of Publication: Spain NLM ID: 8609357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-5848 (Electronic) Linking ISSN: 02133911 NLM ISO Abbreviation: Histol Histopathol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1699-5848
DOI:10.14670/HH-18-953