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Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.

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Title: Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.
Authors: Yang CC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Yeh JN; Institute of Nephrology and Blood Purification, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.; Department of Cardiology, The First Affiliated Hospital, Jinan University, Guangzhou, China., Hsu TW; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Chiang JY; Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan., Cheng BC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan., Sung PH; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net., Wu SC; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Post-Baccalaureate Program in Nursing, Asia University, Taichung, Taiwan., Huang CR; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Shao PL; Department of Nursing, Asia University Taichung, Taiwan. m8951016@gmail.com., Yip HK; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net.; Department of Medical Research, China Medical University Hospital, China Medical University, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Source: Histology and histopathology [Histol Histopathol] 2026 Feb; Vol. 41 (2), pp. 319-337. Date of Electronic Publication: 2025 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Histology and Histopathology Country of Publication: Spain NLM ID: 8609357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-5848 (Electronic) Linking ISSN: 02133911 NLM ISO Abbreviation: Histol Histopathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.
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  Data: <searchLink fieldCode="AU" term="%22Yang+CC%22">Yang CC</searchLink>; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+JN%22">Yeh JN</searchLink>; Institute of Nephrology and Blood Purification, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.; Department of Cardiology, The First Affiliated Hospital, Jinan University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hsu+TW%22">Hsu TW</searchLink>; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+JY%22">Chiang JY</searchLink>; Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+BC%22">Cheng BC</searchLink>; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sung+PH%22">Sung PH</searchLink>; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net.<br /><searchLink fieldCode="AU" term="%22Wu+SC%22">Wu SC</searchLink>; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.; Post-Baccalaureate Program in Nursing, Asia University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CR%22">Huang CR</searchLink>; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shao+PL%22">Shao PL</searchLink>; Department of Nursing, Asia University Taichung, Taiwan. m8951016@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yip+HK%22">Yip HK</searchLink>; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. han.gung@msa.hinet.net.; Department of Medical Research, China Medical University Hospital, China Medical University, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%228609357%22">Histology and histopathology</searchLink> [Histol Histopathol] 2026 Feb; Vol. 41 (2), pp. 319-337. <i>Date of Electronic Publication: </i>2025 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Histology+and+Histopathology%22">Histology and Histopathology </searchLink><i>Country of Publication: </i>Spain <i>NLM ID: </i>8609357 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1699-5848 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202133911%22">02133911 </searchLink><i>NLM ISO Abbreviation: </i>Histol Histopathol <i>Subsets: </i>MEDLINE
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        Value: 10.14670/HH-18-953
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      – Code: eng
        Text: English
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        StartPage: 319
    Titles:
      – TitleFull: Empagliflozin protected kidney function in CKD rat through suppressing hypoxic and fibrotic signalings mediated inflammation and EMT.
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            NameFull: Yang CC
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            NameFull: Yeh JN
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            – D: 01
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              Text: 2026 Feb
              Type: published
              Y: 2026
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              Value: 1699-5848
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              Value: 41
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