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A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics.

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Title: A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics.
Authors: Ríos de Los Ríos Reséndiz J; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Herrmann-Sim F; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Wilkesmann L; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Helm D; Proteomics Core Facility, German Cancer Research Center (DKFZ), 69120, Heidelberg, Heidelberg, Germany., Schneider M; Proteomics Core Facility, German Cancer Research Center (DKFZ), 69120, Heidelberg, Heidelberg, Germany., Campione G; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Plügge K; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Greiner G; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Lazaro García L; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Karlsruhe Institute of Technology, 76131, Karlsruhe, Germany., Berker J; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Richter K; Electron Microscopy Core Facility, German Cancer Research Center (DKFZ), 69120, Heidelberg, Heidelberg, Germany., Zielske L; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Hofmann WK; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany., Clemm von Hohenberg K; Junior Clinical Cooperation Unit Translational Lymphoma Research, German Cancer Research Center (DKFZ) Heidelberg, 68169, Mannheim, Germany. k.clemm@dkfz-heidelberg.de.; Department of Hematology and Oncology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany. k.clemm@dkfz-heidelberg.de.
Source: Scientific reports [Sci Rep] 2025 Jul 07; Vol. 15 (1), pp. 24292. Date of Electronic Publication: 2025 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-08366-8