Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers.
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| Title: | Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers. |
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| Authors: | Doggett K; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia. doggett.k@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia. doggett.k@wehi.edu.au., Morgan KJ; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Olthof AM; Physiology and Neurobiology Department, University of Connecticut, Storrs, CT, 06269, USA.; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Mieruszynski S; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Williams BB; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Garnham AL; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Milevskiy MJG; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Whitehead L; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Coates J; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Buchert M; Cancer and Inflammation Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.; La Trobe University School of Cancer Medicine, Heidelberg, VIC, 3084, Australia., O'Donoghue RJJ; Cancer and Inflammation Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.; La Trobe University School of Cancer Medicine, Heidelberg, VIC, 3084, Australia., Hall TE; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, 4072, Australia., Putoczki TL; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Ernst M; Cancer and Inflammation Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.; La Trobe University School of Cancer Medicine, Heidelberg, VIC, 3084, Australia., Sutherland KD; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia., Kanadia RN; Physiology and Neurobiology Department, University of Connecticut, Storrs, CT, 06269, USA.; Institute for Systems Genomics, University of Connecticut, Storrs, CT, 06269, USA., Heath JK; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia. |
| Source: | EMBO reports [EMBO Rep] 2025 Aug; Vol. 26 (15), pp. 3937-3969. Date of Electronic Publication: 2025 Jul 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.1038/s44319-025-00511-8 |
