Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life.
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| Title: | Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life. |
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| Authors: | Wu QC; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA., Lee J; Cell Design Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA., Swaminathan A; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Winward A; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Hwang Y; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Socolovsky M; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Way JC; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, 201 Brookline Avenue, Boston, MA 02215, USA.; Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA., Klein AM; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA. |
| Source: | Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2025 Jan 10; Vol. 38. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101186484 Publication Model: Print Cited Medium: Internet ISSN: 1741-0134 (Electronic) Linking ISSN: 17410126 NLM ISO Abbreviation: Protein Eng Des Sel Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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