The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models.
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| Title: | The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models. |
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| Authors: | Kyula-Currie J; The Institute of Cancer Research, London, UK. joan.kyula@icr.ac.uk., Roulstone V; The Institute of Cancer Research, London, UK., Wright J; The Institute of Cancer Research, London, UK., Butera F; The Institute of Cancer Research, London, UK., Legrand A; The Institute of Cancer Research, London, UK., Elliott R; The CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research, London, UK., McLaughlin M; The Institute of Cancer Research, London, UK., Bozhanova G; The Institute of Cancer Research, London, UK., Krastev D; The CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research, London, UK., Pettitt S; The CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research, London, UK., Tenev T; The Institute of Cancer Research, London, UK., Dillon M; The Institute of Cancer Research, London, UK., Foo S; The Institute of Cancer Research, London, UK., Patin EC; The Institute of Cancer Research, London, UK., Jennings V; The Institute of Cancer Research, London, UK., Chan Wah Hak C; The Institute of Cancer Research, London, UK., Appleton E; The Institute of Cancer Research, London, UK., Wongariyapak A; The Institute of Cancer Research, London, UK., Pedersen M; The Institute of Cancer Research, London, UK., Rullan A; The Institute of Cancer Research, London, UK., Choudhary J; The Institute of Cancer Research, London, UK., Bakal C; The Institute of Cancer Research, London, UK., Meier P; The Institute of Cancer Research, London, UK., Lord CJ; The CRUK Gene Function Laboratory and Breast Cancer Now Toby Robins Research, London, UK., Melcher A; The Institute of Cancer Research, London, UK., Harrington KJ; The Institute of Cancer Research, London, UK. |
| Source: | Nature communications [Nat Commun] 2025 Jul 08; Vol. 16 (1), pp. 6299. Date of Electronic Publication: 2025 Jul 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-61297-w |
