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Optimization and Evaluation of Colchicine Patch Formulation Based on Box-Behnken Design.

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Title: Optimization and Evaluation of Colchicine Patch Formulation Based on Box-Behnken Design.
Authors: Dong W; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China.; Suzhou Yike New Creation Scientific Instrument CO. LTD, Jiangsu, 215300, China., Feng J; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China., Liu X; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China., Qu J; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China., Li C; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China., Li L; Suzhou Yike New Creation Scientific Instrument CO. LTD, Jiangsu, 215300, China. lilian@sdu.edu.cn.; NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Shandong, 250012, China. lilian@sdu.edu.cn., Zhang S; Suzhou Yike New Creation Scientific Instrument CO. LTD, Jiangsu, 215300, China. zsn@tasly.com.; Tasly Pharmaceut Grp CO. LTD, State Key Lab Core Technol Innovat Chinese Med, Tianjin, 300410, China. zsn@tasly.com., Li W; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. wshlwl@tjutcm.edu.cn.; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China. wshlwl@tjutcm.edu.cn.; Suzhou Yike New Creation Scientific Instrument CO. LTD, Jiangsu, 215300, China. wshlwl@tjutcm.edu.cn.
Source: AAPS PharmSciTech [AAPS PharmSciTech] 2025 Jul 08; Vol. 26 (6), pp. 188. Date of Electronic Publication: 2025 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1530-9932
DOI:10.1208/s12249-025-03158-9