Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling.

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Title: Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling.
Authors: Knight B; Johnson & Johnson, San Diego, CA, USA. bknight3@its.jnj.com., Tammara B; Johnson & Johnson, Spring House, PA, USA., Modi NB; Protagonist Therapeutics, Inc, Newark, CA, USA., Dallas S; Johnson & Johnson, Spring House, PA, USA., Mardirosian S; Johnson & Johnson, Spring House, PA, USA., Wang J; Johnson & Johnson, Spring House, PA, USA., Laenen A; Johnson & Johnson, Beerse, Belgium., Leclercq L; Johnson & Johnson, Beerse, Belgium., DiLoreto K; Johnson & Johnson, Spring House, PA, USA., Adriaenssen L; Johnson & Johnson, Beerse, Belgium., Moss D; Johnson & Johnson, Beerse, Belgium., Polidori D; Johnson & Johnson, San Diego, CA, USA., Chaudhuri SR; Johnson & Johnson, San Diego, CA, USA., Park S; Johnson & Johnson, Spring House, PA, USA., Sensenhauser C; Johnson & Johnson, Spring House, PA, USA., Ndifor A; Johnson & Johnson, San Diego, CA, USA., Sukumaran S; Johnson & Johnson, Spring House, PA, USA., Baguet T; Johnson & Johnson, Beerse, Belgium., Shi Y; Johnson & Johnson, Spring House, PA, USA., Patel S; Johnson & Johnson, Spring House, PA, USA., Geist B; Johnson & Johnson, Spring House, PA, USA., Fourie A; Johnson & Johnson, San Diego, CA, USA., Patch R; Johnson & Johnson, Spring House, PA, USA., Sun C; Johnson & Johnson, Spring House, PA, USA.; Pinnacle Medicines, Doylestown, PA, USA., Barros SA; Johnson & Johnson, Spring House, PA, USA., Somani S; Johnson & Johnson, Spring House, PA, USA.; Pinnacle Medicines, Doylestown, PA, USA., Monshouwer M; Johnson & Johnson, Beerse, Belgium.
Source: Dermatology and therapy [Dermatol Ther (Heidelb)] 2025 Sep; Vol. 15 (9), pp. 2495-2520. Date of Electronic Publication: 2025 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Healthcare Communications Country of Publication: Switzerland NLM ID: 101590450 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8210 (Print) NLM ISO Abbreviation: Dermatol Ther (Heidelb) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2193-8210
DOI:10.1007/s13555-025-01454-7