Genesis of additional open state zones in the extended polyQ tract of the ATXN2 gene depends on its length and interruptions localization.

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Title: Genesis of additional open state zones in the extended polyQ tract of the ATXN2 gene depends on its length and interruptions localization.
Authors: Drobotenko MI; Scientific Department, Kuban State University, Krasnodar, Russian Federation., Velázquez-Pérez L; President's Office, Cuban Academy of Sciences, La Habana, Cuba., Dorohova АA; Scientific Department, Kuban State University, Krasnodar, Russian Federation; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation. Electronic address: jimack@mail.ru., Lyasota OM; Scientific Department, Kuban State University, Krasnodar, Russian Federation; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation., Hernandez-Caceres JL; Neurodevelopment Branch, Cuban Center for Neurosciences, La Habana, Cuba; Join Institute of Nuclear Research, Dubna, Russian Federation., Rodriguez-Labrada R; Neurodevelopment Branch, Cuban Center for Neurosciences, La Habana, Cuba., Svidlov AA; Scientific Department, Kuban State University, Krasnodar, Russian Federation; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation., Leontyeva OA; Scientific Department, Kuban State University, Krasnodar, Russian Federation., Baryshev MG; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation., Nechipurenko YD; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation; Research Institute for Brain Development and Peak Performance, RUDN University, Moscow, Russian Federation., Dzhimak SS; Scientific Department, Kuban State University, Krasnodar, Russian Federation; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, Rostov-on-Don, Russian Federation.
Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Oct; Vol. 772, pp. 110531. Date of Electronic Publication: 2025 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1096-0384
DOI:10.1016/j.abb.2025.110531