Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control.

Saved in:
Bibliographic Details
Title: Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control.
Authors: Rodschinka G; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany., Forcelloni S; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany., Kühner FM; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany., Wani S; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany., Riemenschneider H; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Behrens A; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany., Nedialkova DD; Mechanisms of Protein Biogenesis Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany. nedialkova@biochem.mpg.de.; Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany. nedialkova@biochem.mpg.de.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Oct; Vol. 32 (10), pp. 1932-1946. Date of Electronic Publication: 2025 Jul 11.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1545-9985
DOI:10.1038/s41594-025-01616-3