KRASG12D selective VHL-PROTAC with sparing KRASWT and other KRAS mutants.
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| Title: | KRASG12D selective VHL-PROTAC with sparing KRASWT and other KRAS mutants. |
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| Authors: | Jeon E; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim C; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea., Ko M; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim TK; Department of Internal Medicine, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Bae J; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea., Oh JW; Department of Applied Chemistry, Institute of Natural Science, Kyung Hee University, Yongin, Republic of Korea; Department of Biomedical Science and Technology, Kyung Hee Medical Science Research Institute, Kyung Hee University, Seoul, Republic of Korea., Kim KP; Department of Applied Chemistry, Institute of Natural Science, Kyung Hee University, Yongin, Republic of Korea; Department of Biomedical Science and Technology, Kyung Hee Medical Science Research Institute, Kyung Hee University, Seoul, Republic of Korea., Kim HS; Department of Internal Medicine, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Sim T; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea; Graduate School of Clinical Drug Discovery & Development, Yonsei University College of Medicine, Seoul, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: TBSIM@yuhs.ac. |
| Source: | European journal of medicinal chemistry [Eur J Med Chem] 2025 Nov 05; Vol. 297, pp. 117928. Date of Electronic Publication: 2025 Jul 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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