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Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies.

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Title: Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies.
Authors: Buck SA; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA., Malankhanova T; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Ma EB; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA., Yim S; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA., Pratt HW; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA., Ervin J; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke/UNC Alzheimer's Disease Research Center, Durham, NC, 27710, USA., Wang SJ; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke/UNC Alzheimer's Disease Research Center, Durham, NC, 27710, USA., Cohen TJ; Department of Neurology, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, 27599, USA.; UNC Neuroscience Center, University of North Carolina, Chapel Hill, NC, 27599, USA., West AB; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA., Sanders LH; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 09. Date of Electronic Publication: 2025 Jun 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 40661559
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies.
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  Data: <searchLink fieldCode="AU" term="%22Buck+SA%22">Buck SA</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Malankhanova+T%22">Malankhanova T</searchLink>; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Ma+EB%22">Ma EB</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Yim+S%22">Yim S</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Pratt+HW%22">Pratt HW</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Ervin+J%22">Ervin J</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke/UNC Alzheimer's Disease Research Center, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Wang+SJ%22">Wang SJ</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke/UNC Alzheimer's Disease Research Center, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+TJ%22">Cohen TJ</searchLink>; Department of Neurology, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, 27599, USA.; UNC Neuroscience Center, University of North Carolina, Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22West+AB%22">West AB</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+LH%22">Sanders LH</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University, Durham, NC, 27710, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Jun 09. <i>Date of Electronic Publication: </i>2025 Jun 09.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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      – Type: doi
        Value: 10.1101/2025.06.06.658328
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        Text: English
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      – TitleFull: Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies.
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          Dates:
            – D: 09
              M: 06
              Text: 2025 Jun 09
              Type: published
              Y: 2025
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