Immune, Developmental, and Synaptic Pathways Define Bipolar Disorder Clinical Heterogeneity.

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Title: Immune, Developmental, and Synaptic Pathways Define Bipolar Disorder Clinical Heterogeneity.
Authors: van der Veen T, Tesfaye M, Yang JMK, Boltz T, David FS, Crinion S, Koromina M, Andlauer TFM, Bigdeli TB, Coombes BJ, Greenwood TA, Panagiotaropoulou G, Parker N, Sung H, Bass N, Coleman JRI, Guzman-Parra J, Kalman JL, McGrouther CC, Mitchell BL, Rangan AV, Scott K, Shadrin A, Smith DJ, Vreeker A, Adorjan K, Albani D, Alemany S, Alliey-Rodriguez N, Antoniou A, Bauer M, Beins EC, Boks MP, Bosch R, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Byerley W, Cabana-Domínguez J, Cairns MJ, Carpiniello B, Casas M, Cervantes P, Chatzinakos C, Clarke TK, Claus I, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, DePaulo JR, Degenhardt F, Djurovic S, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Hahn T, Marian L, Harder A, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Jamain S, Jonsson L, Kennedy JL, Kittel-Schneider S, Knowles JA, Koch E, Kogevinas M, Kranz TM, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lind PA, Lucae S, Lundberg M, MacIntyre DJ, Maier W, Maihofer AX, Malaspina D, Manchia M, Maratou E, Martinsson L, McInnis MG, McKay JD, Medeiros H, Meyer-Lindenberg A, Millischer V, Morris DW, Moutsatsou P, Mühleisen TW, 'Donovan CO, Olsen CM, Papiol S, Pardiñas AF, Perry A, Pfennig A, Pisanu C, Potash JB, Quested D, Rapaport MH, Regeer EJ, Rice JP, Rivera M, Schulte EC, Senner F, Shilling PD, Sindermann L, Sirignano L, Siskind D, Slaney C, Smeland OB, Sobell JL, Artigas MS, Stein DJ, Stein F, Swiatkowska B, Thorp JG, Toma C, Tondo L, Tooney PA, Vawter MP, Vedder H, Walters JTR, Witt SH, Young AH, Zandi PP, Zillich L, Adolfsson R, Alfredsson L, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Biernacka JM, Blackwood D, Boehnke M, Breen G, Carr VJ, Catts S, Cichon S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Hauser J, Henskens FA, Hjerling-Leffler J, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kircher T, Kirov G, Kobayashi N, Landén M, Leboyer M, Lenger M, Li QS, Lissowska J, Loughland C, Luykx JJ, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, Medland SE, Melle I, Mitchell PB, Morken G, Myers RM, Möser C, Müller-Myhsok B, Neale BM, Nievergelt CM, Nurnberger JI, Nöthen MM, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato CN, Pato MT, Patrinos GP, Pawlak JM, Perlis R, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Smoller JW, Squassina A, Stahl EA, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert CS, Weickert TW, Whiteman DC, Alda M, Ophoff RA, O'Connell KS, Mullins N, Forstner AJ, Grigoroiu-Serbanescu M, Edenberg HJ, McMahon FJ, Andreassen OA, Di Florio A, McQuillin A
Corporate Authors: Estonian Biobank research team, Genomic Psychiatry Cohort (GPC) Investigators, HUNT All-In Psychiatry, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Jun 27. Date of Electronic Publication: 2025 Jun 27.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.1101/2025.06.23.25330155