TDP-43 pathology induces CD8+ T cell activation through cryptic epitope recognition.
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| Title: | TDP-43 pathology induces CD8+ T cell activation through cryptic epitope recognition. |
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| Authors: | Chizari S; Department of Bioengineering, University of Pennsylvania, Philadelphia, USA., Zanovello M; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Kong S; Department of Bioengineering, University of Pennsylvania, Philadelphia, USA., Saigal V; Department of Bioengineering, University of Pennsylvania, Philadelphia, USA., Brown AL; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Turchetti V; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Zampedri L; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Skorupinska I; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Minicuci GM; Padua Neuroscience Centre, University of Padua, Italy., Paron F; International Centre for Genetic Engineering and Biotechnology., Tonin P; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy., Marchetto G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy., Li Z; Center for Alzheimer's and Related Dementias, NIH., Colón-Mercado JM; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Dattilo D; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Barattucci S; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Gatt A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Qi A; Center for Alzheimer's and Related Dementias, NIH., Hanna M; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Ward M; Center for Alzheimer's and Related Dementias, NIH.; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Petrucelli L; Mayo Clinic College of Medicine and Science, Mayo Clinic, USA., Romano M; Department of Life Sciences, University of Trieste, Italy., Vattemi G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy., Buratti E; International Centre for Genetic Engineering and Biotechnology., Malapsina A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Merve A; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK., Machado PM; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK.; NIHR University College London Hospitals Biomedical Research Centre., Soraru G; Padua Neuroscience Centre, University of Padua, Italy., Fratta P; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, UK.; The Francis Crick Institute, London, UK., Jiang N; Department of Bioengineering, University of Pennsylvania, Philadelphia, USA.; Penn Institute for Immunology and Immune Health, University of Pennsylvania, Philadelphia.; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia.; Abramson Cancer Center, University of Pennsylvania, Philadelphia.; Institute for RNA Innovation, University of Pennsylvania, Philadelphia.; Penn Center for Precision Engineering for Health, University of Pennsylvania, Philadelphia, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 14. Date of Electronic Publication: 2025 Jul 14. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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