Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy.

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Title: Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy.
Authors: McGeachan RI; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; The University of Edinburgh Hospital for Small Animals, Edinburgh, UK., Keavey L; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Simzer EM; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Chang YY; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Rose JL; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Spires-Jones MP; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Gilmore M; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Holt K; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Meftah S; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Ravingerova N; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Scutariu C; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Taylor LW; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., King D; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Tzioras M; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; Scottish Brain Sciences, Edinburgh, UK., Tulloch J; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK., Booker SA; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK., Liaquat I; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK., Hindley-Pollock N; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Geary B; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Smith C; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK., Brennan PM; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK., Durrant CS; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK. claire.durrant@ed.ac.uk.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK. claire.durrant@ed.ac.uk., Spires-Jones TL; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK. tara.spires-jones@ed.ac.uk.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK. tara.spires-jones@ed.ac.uk.
Source: Nature neuroscience [Nat Neurosci] 2025 Aug; Vol. 28 (8), pp. 1622-1634. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
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  Data: Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy.
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  Data: <searchLink fieldCode="AU" term="%22McGeachan+RI%22">McGeachan RI</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; The University of Edinburgh Hospital for Small Animals, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Keavey+L%22">Keavey L</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Simzer+EM%22">Simzer EM</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Chang+YY%22">Chang YY</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Rose+JL%22">Rose JL</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Spires-Jones+MP%22">Spires-Jones MP</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gilmore+M%22">Gilmore M</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Holt+K%22">Holt K</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Meftah+S%22">Meftah S</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ravingerova+N%22">Ravingerova N</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Scutariu+C%22">Scutariu C</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Taylor+LW%22">Taylor LW</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22King+D%22">King D</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tzioras+M%22">Tzioras M</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; Scottish Brain Sciences, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tulloch+J%22">Tulloch J</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Booker+SA%22">Booker SA</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Liaquat+I%22">Liaquat I</searchLink>; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hindley-Pollock+N%22">Hindley-Pollock N</searchLink>; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Geary+B%22">Geary B</searchLink>; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Brennan+PM%22">Brennan PM</searchLink>; The University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Durrant+CS%22">Durrant CS</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK. claire.durrant@ed.ac.uk.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK. claire.durrant@ed.ac.uk.<br /><searchLink fieldCode="AU" term="%22Spires-Jones+TL%22">Spires-Jones TL</searchLink>; The University of Edinburgh Centre for Discovery Brain Sciences, Edinburgh, UK. tara.spires-jones@ed.ac.uk.; UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK. tara.spires-jones@ed.ac.uk.
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