Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.

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Title: Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.
Authors: Simonson AW; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chao MC; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hood LE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Donlan RA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Hopkins F; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Chase MR; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Vickers AJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Callendrello A; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Klein E; Division of Animal Laboratory Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Borish HJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Malin M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lin PL; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, USA., Fortune SM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 31. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.
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  Data: <searchLink fieldCode="AU" term="%22Simonson+AW%22">Simonson AW</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chao+MC%22">Chao MC</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hood+LE%22">Hood LE</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Donlan+RA%22">Donlan RA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hopkins+F%22">Hopkins F</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chase+MR%22">Chase MR</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vickers+AJ%22">Vickers AJ</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Callendrello+A%22">Callendrello A</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Klein+E%22">Klein E</searchLink>; Division of Animal Laboratory Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Borish+HJ%22">Borish HJ</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Malin+M%22">Malin M</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Maiello+P%22">Maiello P</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Scanga+CA%22">Scanga CA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+PL%22">Lin PL</searchLink>; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fortune+SM%22">Fortune SM</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Flynn+JL%22">Flynn JL</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
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        Value: 10.1101/2025.07.08.663727
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        Text: English
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              Text: 2025 Jul 31
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