Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes.

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Title: Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes.
Authors: Singh PJ; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; US Department of Veterans Affairs, Veterans Affairs Medical Center, Fayetteville, AR, USA., Verma B; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Wells A; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Mendes CC; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Dunn D; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Chen YN; Department of Life Sciences, National Central University, Taoyuan City, Taiwan., Oh J; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Blincowe L; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Wainwright SM; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK., Fischer R; Target Discovery Institute, University of Oxford, Oxford, UK., Fan SJ; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Life Sciences, National Central University, Taoyuan City, Taiwan., Harris AL; Department of Oncology, University of Oxford, Oxford, UK., Goberdhan DCI; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK., Wilson C; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK. clive.wilson@dpag.ox.ac.uk.
Source: The EMBO journal [EMBO J] 2025 Aug; Vol. 44 (16), pp. 4443-4472. Date of Electronic Publication: 2025 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
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  Data: Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes.
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  Data: <searchLink fieldCode="AU" term="%22Singh+PJ%22">Singh PJ</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; US Department of Veterans Affairs, Veterans Affairs Medical Center, Fayetteville, AR, USA.<br /><searchLink fieldCode="AU" term="%22Verma+B%22">Verma B</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wells+A%22">Wells A</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mendes+CC%22">Mendes CC</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dunn+D%22">Dunn D</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Chen+YN%22">Chen YN</searchLink>; Department of Life Sciences, National Central University, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Oh+J%22">Oh J</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Blincowe+L%22">Blincowe L</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wainwright+SM%22">Wainwright SM</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Fischer+R%22">Fischer R</searchLink>; Target Discovery Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Fan+SJ%22">Fan SJ</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; Department of Life Sciences, National Central University, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Harris+AL%22">Harris AL</searchLink>; Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Goberdhan+DCI%22">Goberdhan DCI</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.; Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wilson+C%22">Wilson C</searchLink>; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK. clive.wilson@dpag.ox.ac.uk.
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