LRRK2 kinase modulates glucose-stimulated insulin secretion via RAB8 phosphorylation and ciliogenesis.
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| Title: | LRRK2 kinase modulates glucose-stimulated insulin secretion via RAB8 phosphorylation and ciliogenesis. |
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| Authors: | Dule N; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy., Marku A; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy., Galli A; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy., Pischedda F; CIBIO, Università Degli Studi di Trento, Dulbecco Telethon Institute, Trento, Italy., Lama A; CIBIO, Università Degli Studi di Trento, Dulbecco Telethon Institute, Trento, Italy., Castagna M; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy., Marciani P; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy., Bertuzzi F; Niguarda Cà Granda Hospital, Milan, Italy., Piccoli G; CIBIO, Università Degli Studi di Trento, Dulbecco Telethon Institute, Trento, Italy., Perego C; Laboratory of Molecular and Cellular Physiology, Department of Excellence of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Trentacoste 2, 20134, Milan, Italy. carla.perego@unimi.it. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Jul 17; Vol. 82 (1), pp. 276. Date of Electronic Publication: 2025 Jul 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-025-05810-w |
