A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis.

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Title: A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis.
Authors: Zhang H; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Ma J; Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China., Hou C; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Luo X; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Zhu S; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Peng Y; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Peng C; GW Cancer Center, Department of Biochemistry & Molecular Medicine, George Washington University, Washington DC, USA., Li P; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA.; Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China., Meng H; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Xia Y; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Jiang Z; Flow Cytometry and Cell Sorting Center, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Modepalli S; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Duttargi A; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Kupfer GM; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA., Cai M; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Zhang H; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, China. tracyheng0719@163.com., Ma J; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA. junfeng.ma@georgetown.edu., Li J; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, China. juanjuan.li@whu.edu.cn., Han S; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. shan87@xjtu.edu.cn., Pei H; Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA. huadong.pei@georgetown.edu.
Source: Nature cell biology [Nat Cell Biol] 2025 Aug; Vol. 27 (8), pp. 1288-1300. Date of Electronic Publication: 2025 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4679
DOI:10.1038/s41556-025-01722-w